The Zymo-Spin IC-XL column can be used either in microcentrifuges or on vacuum manifolds for the purification of DNA and/or RNA. The Zymo-Spin IC-XL features durable polypropylene construction and contains a unique silica-based matrix that allows purification of up to 10 ug of DNA, and 20 ug of RNA, in ≥ 10 ul eluate. Capacity is 1 ml.