PureRec Duplex-Specific Nuclease (DSN)
1000 Units
Zymo E1020-1000

PureRec Duplex-Specific Nuclease (DSN) <br> 1000 Units <br> Zymo E1020-1000
PureRec Duplex-Specific Nuclease (DSN)
1000 Units
Zymo E1020-1000
Item# Zymo-E1020-1000
Regular price: $650.00
Sale price: $599.99
Quantity: 

Product Description

PureRec Duplex-Specific Nuclease (DSN) <br> 1000 Units <br> Zymo E1020-1000
PureRec Duplex-Specific Nuclease (DSN)
1000 Units
Zymo E1020-1000

HIGHLIGHTS :

Highest Specificity: Selectively digests dsDNA and DNA in DNA-RNA hybrids; virtually inactive towards ssDNA or RNA. Premium Purity: RNase-free, protease-free, and animal-free. Thermostable: Able to withstand high temperatures without denaturation or loss in activity.

DESCRIPTION :

PureRec Duplex-Specific Nuclease (DSN) is an endonuclease that selectively digests double-stranded DNA (dsDNA) and DNA in DNA-RNA hybrids, exhibiting virtually no activity towards single-stranded DNA (ssDNA) or RNA.

It can discriminate between perfectly matched and non-matched short DNA duplexes. To catalyze cleavage, DSN needs a minimum of 10 bp dsDNA or 15 bp perfectly matched DNA-RNA duplex.

This enzymatic function is reliant upon the presence of Mg2+ ions, with a recommended concentration of 5 mM for most applications.

PureRec DSN is overexpressed and extensively purified from a non-animal source and is free of non-specific nucleases or RNases.

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APPLICATION :

Remove gDNA and DNA in DNA:RNA hybrids for protein or RNA preparations. Reduce abundant rRNA and globin transcripts to enhance next-generation sequencing (NGS) libraries. Achieve precise single-nucleotide polymorphism (SNP) detection with minimal off-target effects. Enhance signal amplification for accurate virus detection. Improve detection of miRNA and biomarkers.

Accessories

PureRec Duplex-Specific Nuclease (DSN)<br> 200 Units <br>  Zymo E1020-200
Regular price: $185.00
Sale price: $174.99
PureRec Duplex-Specific Nuclease (DSN)
200 Units
Zymo E1020-200
Zymo-E1020-200
Quantity: 
PureRec Duplex-Specific Nuclease (DSN) <br> 1000 Units <br> Zymo E1020-1000
Regular price: $650.00
Sale price: $599.99
PureRec Duplex-Specific Nuclease (DSN)
1000 Units
Zymo E1020-1000
Zymo-E1020-1000
Quantity: