Nystatin is an antifungal polyene antibiotic that is effective against a wide range of fungi, including yeast and molds. It works by binding to the fungal cell membrane, disrupting its integrity and leading to leakage of cellular contents.
Nystatin is particularly useful in preventing and treating fungal contamination in cell cultures, making it a valuable tool in microbiological research. Researchers often use Nystatin to maintain aseptic conditions in cell culture experiments.
It is added to growth media to prevent the overgrowth of fungi that could potentially compromise the integrity of cell lines and experimental results. It is selective for fungi and has minimal toxicity to mammalian cells at effective antifungal concentrations.