Geldanamycin,
from Streptomyces Hygroscopicus,
1 Milligrams
RPI-G40040-0.001

Geldanamycin,
from Streptomyces Hygroscopicus,
1 Milligrams
RPI-G40040-0.001

Research or further manufacturing use only, not for food or drug use.

Molecular Weight: 560.6

Chemical Formula: C29H40N2O9

Solubility: DMSO

Storage Temperature: -20°C

Geldanamycin is a naturally occurring antibiotic derived from the bacterium Streptomyces hygroscopicus. It has gained significance due to its role as an inhibitor of heat shock protein 90 (Hsp90), a molecular chaperone involved in protein folding and stabilization.

Geldanamycin is often used as a research tool to study cellular processes that are dependent on Hsp90. By inhibiting Hsp90, geldanamycin affects the stability and function of various client proteins associated with cell signaling, growth, and survival.

Researchers use geldanamycin to investigate the role of Hsp90 in the context of cancer, as many oncoproteins require Hsp90 for proper folding and stability.