G-418 Disulfate
50 mg/ml Solution, 10 Milliliters
RPI-G64500-10.0

G-418 Disulfate
50 mg/ml Solution, 10 Milliliters
RPI-G64500-10.0

Research or further manufacturing use only, not for food or drug use.

Molecular Weight: 692.7

Chemical Formula: C20H40N4O10 • 2H2SO4

Solubility: Water

Storage Temperature: 2-8°C

G-418 Disulfate, Solution is a widely used antibiotic in the life science marketplace. It is commonly employed as a selective agent in cell culture and molecular biology experiments. G-418, also known as Geneticin, is a member of the aminoglycoside family of antibiotics.

In the life science field, G-418 Disulfate Solution is primarily utilized for the selection and maintenance of cells that have been genetically modified to express the neomycin resistance gene. This resistance gene allows the cells to survive in the presence of G-418, while non-modified cells are unable to survive.

Researchers and scientists working in areas such as molecular biology, genetic engineering, and biotechnology rely on G-418 Disulfate Solution for various applications. It is frequently used as a selectable marker in plasmids and other vectors to ensure that only cells carrying the desired genetic material survive and proliferate.

G-418 Disulfate Solution is compatible with a wide range of mammalian, insect, and plant cell lines, making it versatile for different cell culture systems. It is typically added to the culture medium at specific concentrations to inhibit the growth of non-resistant cells while allowing the growth of genetically modified cells.

Moreover, G-418 Disulfate Solution can be used to generate stable cell lines expressing recombinant proteins or studying gene function. Its broad-spectrum activity and compatibility with different cell types make it an important tool for researchers studying molecular mechanisms, protein expression, and genetic manipulation.