Allopurinol inhibits the enzyme xanthine oxidase, which is involved in the production of uric acid. Researchers may use allopurinol to manipulate uric acid levels in experimental settings, allowing them to study the metabolism and physiological effects of uric acid in various tissues and organs.
Allopurinol may be used in studies examining drug interactions or combination therapies. By understanding how allopurinol interacts with other medications or compounds, researchers can optimize treatment strategies and minimize potential adverse effects.
Allopurinol's mechanism of action extends beyond its inhibition of xanthine oxidase. Researchers may utilize allopurinol to probe the downstream effects of xanthine oxidase inhibition, including alterations in oxidative stress, inflammation, and purine metabolism pathways.