17-DMAG
[17-Dimethylaminoethylamino-17-demethoxygeldanamycin],
5 Milligrams
RPI-D26100-0.005

17-DMAG
[17-Dimethylaminoethylamino-17-demethoxygeldanamycin],
5 Milligrams
RPI-D26100-0.005

Research or further manufacturing use only, not for food or drug use.

Common Name: 17-Dimethylaminoethylamino-17-demethoxygeldanamycin

CAS Number: 467214-20-6

Molecular Weight: 616.8

Chemical Formula: C32H48N4O8

Solubility: DMSO, Ethanol

Storage Temperature: -20°C

17-DMAG (17-Dimethylaminoethylamino-17-demethoxygeldanamycin) is a synthetic derivative of the antibiotic geldanamycin. It belongs to the class of compounds known as Hsp90 (heat shock protein 90) inhibitors. Heat shock proteins, including Hsp90, play a role in cellular processes and are involved in the folding and stabilization of other proteins, known as client proteins.

The primary function of 17-DMAG is to inhibit the activity of Hsp90, leading to the degradation of client proteins that are dependent on Hsp90 for stability. Many of these client proteins are involved in signaling pathways and cellular processes associated with cancer, making 17-DMAG a valuable compound in cancer research.