Tunicamycin,
10 Milligrams
RPI-T22500-0.01

Tunicamycin, <br> 10 Milligrams <br> RPI-T22500-0.01
Tunicamycin,
10 Milligrams
RPI-T22500-0.01
Item# RPI-T22500-0-01
Regular price: $460.00
Sale price: $426.99
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Product Description

Tunicamycin, <br> 10 Milligrams <br> RPI-T22500-0.01
Tunicamycin,
10 Milligrams
RPI-T22500-0.01

Research or further manufacturing use only, not for food or drug use.

Molecular Weight: 844.9

Chemical Formula: C39H64N4O16

Solubility: DMSO

Storage Temperature: 2-8C

Tunicamycin is a nucleoside antibiotic that inhibits the biosynthesis of N-linked glycoproteins. It inhibits the formation of N-glycosidic linkages during the early steps of protein glycosylation. Also, it interferes with the transfer of N-acetylglucosamine-1-phosphate to dolichol phosphate, a crucial step in the synthesis of lipid-linked oligosaccharides. As a result, the glycosylation process in the endoplasmic reticulum is disrupted.

Widely used as a tool in cell biology and biochemistry to study protein glycosylation. It helps researchers investigate the effects of impaired glycosylation on cellular processes. This antibiotic induces endoplasmic reticulum (ER) stress by disrupting protein folding and glycosylation in the ER. This property is utilized in studies focused on understanding ER stress responses and unfolded protein response pathways.

Tunicamycin is a valuable tool for investigating the role of protein glycosylation in cellular functions and for inducing ER stress for studies related to unfolded protein responses.