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Bafilomycin A1,
1 Milligram
RPI-B40500-0.001
1 Milligram
RPI-B40500-0.001
Product Description
Bafilomycin A1,
1 Milligram
RPI-B40500-0.001
Research or further manufacturing use only, not for food or drug use.
Molecular Weight: 622.8
Chemical Formula: C35H58O9
Solubility: Soluble in ethanol or methanol: 0.1 mg/ml; in DMSO: 5 mg/ml. Poor water solubility.
Storage Temperature: -20°C
Bafilomycin A1 is a potent and selective inhibitor of the vacuolar-type H+-ATPase (V-ATPase), an enzyme responsible for maintaining acidic pH in cellular compartments such as lysosomes and endosomes.
In the life science field, Bafilomycin A1 is primarily used as a research tool to investigate the role of V-ATPase and lysosomal acidification in various cellular processes. By inhibiting V-ATPase, Bafilomycin A1 disrupts the acidification of cellular compartments, which in turn affects processes such as protein degradation, autophagy, endocytosis, and vesicular trafficking.
Bafilomycin A1 can be used to study autophagy, a cellular process involved in the degradation and recycling of cellular components. By inhibiting V-ATPase, Bafilomycin A1 blocks the final step of autophagy, preventing the fusion of autophagosomes with lysosomes and thereby inhibiting autophagic degradation.
1 Milligram
RPI-B40500-0.001
Research or further manufacturing use only, not for food or drug use.
Molecular Weight: 622.8
Chemical Formula: C35H58O9
Solubility: Soluble in ethanol or methanol: 0.1 mg/ml; in DMSO: 5 mg/ml. Poor water solubility.
Storage Temperature: -20°C
Bafilomycin A1 is a potent and selective inhibitor of the vacuolar-type H+-ATPase (V-ATPase), an enzyme responsible for maintaining acidic pH in cellular compartments such as lysosomes and endosomes.
In the life science field, Bafilomycin A1 is primarily used as a research tool to investigate the role of V-ATPase and lysosomal acidification in various cellular processes. By inhibiting V-ATPase, Bafilomycin A1 disrupts the acidification of cellular compartments, which in turn affects processes such as protein degradation, autophagy, endocytosis, and vesicular trafficking.
Bafilomycin A1 can be used to study autophagy, a cellular process involved in the degradation and recycling of cellular components. By inhibiting V-ATPase, Bafilomycin A1 blocks the final step of autophagy, preventing the fusion of autophagosomes with lysosomes and thereby inhibiting autophagic degradation.